DepoDur: Efficacy

Deliver Effective Relief

Less overall rescue opioids required 1-5

DepoDur significantly reduced total supplemental opioid use from 24 to 48 hours vs conventional epidural morphine sulfate (MS) injection 5

Some patients required no rescue opioids 1,4

DepoDur is indicated for epidural administration, at the lumbar level, for the treatment of pain following major surgery. DepoDur is administered prior to surgery or after clamping the umbilical cord during elective cesarean delivery. As with all opioids, the most serious side effect of morphine sulfate is respiratory depression, especially in elderly and debilitated patients and in those with compromised respiratory function.

Meet a Mandate for
Patient Comfort

Significant decrease in pain intensity 1-5

DepoDur significantly improved overall pain scores from 24 to 48 hours vs conventional epidural MS injection 5
Significantly lower pain-intensity scores with less use of IV PCA* fentanyl , compared with conventional epidural MS injection, through 48 hours 4,13

*Intravenous patient-controlled analgesia .
Integrated rank scores.

back to top

Important Safety Information

DepoDur is not intended for intrathecal, intravenous, or intramuscular administration. Administration of DepoDur into the thoracic epidural space or higher has not been evaluated and therefore is not recommended. The majority of adverse events were typical opioid-related side effects and would be expected in the surgical populations studied. No statistically significant differences between treatment groups with respect to nausea, pruritus, sedation scores, vomiting episodes, or urinary retention.

More information on safety page.

Please see full Prescribing Information.

Physician Resources Hospital Pharmacy Resources Nurse Resources Full Prescribing Information
Terms and Conditions Privacy Policy Contact Us About EKR Therapeutics