Deliver Effective Relief

Less overall rescue opioids required 1-5

DepoDur significantly reduced total supplemental opioid use from 24 to 48 hours vs conventional epidural morphine sulfate (MS) injection 5

Some patients required no rescue opioids 1,4

DepoDur is indicated for epidural administration, at the lumbar level, for the treatment of pain following major surgery. DepoDur is administered prior to surgery or after clamping the umbilical cord during elective cesarean delivery. As with all opioids, the most serious side effect of morphine sulfate is respiratory depression, especially in elderly and debilitated patients and in those with compromised respiratory function.

Important Safety Information

DepoDur is not intended for intrathecal, intravenous, or intramuscular administration. Administration of DepoDur into the thoracic epidural space or higher has not been evaluated and therefore is not recommended. The majority of adverse events were typical opioid-related side effects and would be expected in the surgical populations studied. No statistically significant differences between treatment groups with respect to nausea, pruritus, sedation scores, vomiting episodes, or urinary retention.

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